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中文人类
C2 - Complement C2
Alias:
CO2
ARMD14
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补体系统经典途径的成分C2是一种血清糖蛋白，其功能是作为补体系统的一部分。激活的C1将C2切割成C2a和C2b。丝氨酸蛋白酶C2a然后与补体因子4b结合，形成C3或C5转化酶。C2缺乏已被报道与某些自身免疫性疾病有关，而此基因中的SNPs与对年龄相关性黄斑变性的易感性的改变有关。此基因定位在染色体6短臂的MHC的III类区域。可选的剪接导致编码不同异构体的多个转录变异体。其他转录变异体已在出版物中描述，但其完整序列尚未确定。[RefSeq，2009年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
C2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
