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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TP73 - Tumor Protein P73
Alias:
P73
CILD47
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码p53家族的一个转录因子成员,参与细胞对压力和发育的反应。它映射到1p36染色体的一个区域,该区域在神经母细胞瘤和其他肿瘤中经常被删除,被认为包含多个肿瘤抑制基因。这个基因是单倍体表达的(可能来自母系等位基因)的实验证据,支持它可能是神经母细胞瘤候选基因的观点。这个基因发现了许多由替代剪接和/或使用替代启动子产生的转录变体,但一些变体的生物学有效性和全长性质尚未确定。[由RefSeq提供,2011年2月]
Related ID:
NCBI:7161
ENSEMBL:ENSG00000078900
HGNC:12003
UNIPROT:O15350
OMIM:601990
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7161
15
14
83686 bp
69.62
44
2
18
31
TP73 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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Mutations
No data available
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Type
Name
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CAS Number
Status
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Link
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References Literature
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IF
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