Log In|Sign Up
中文人类
TNFRSF1B - TNF Receptor Superfamily Member 1B
Alias:
p75
TBPII
TNFBR
TNFR2
CD120b
TNFR1B
TNFR80
TNF-R75
p75TNFR
TNF-R-II
Favorite
这个基因编码的蛋白质是肿瘤坏死因子受体超家族的成员。这个蛋白质和肿瘤坏死因子受体1形成一个异质复合物，介导了两种抗凋亡蛋白质c-IAP1和c-IAP2的招募，这两种蛋白质具有泛素连接酶活性。IAPs在肿瘤坏死因子受体信号传导中的功能尚不清楚，但是c-IAP1被认为通过泛素化和降解介导抗凋亡信号的肿瘤坏死因子受体相关因子2，增强了肿瘤坏死因子诱导的凋亡。小鼠的敲除研究也表明这个蛋白质通过刺激抗氧化途径在保护神经元免于凋亡中发挥作用。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TNFRSF1B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
