人类

TNFAIP6 - TNF Alpha Induced Protein 6

Alias:
TSG6
TSG-6
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种含有透明质酸结合结构域的分泌蛋白质,因此是透明质酸结合蛋白家族的成员。透明质酸结合结构域已知参与细胞外基质稳定性和细胞迁移。这个蛋白质已经证明可以与α抑制子(IαI)形成稳定的复合物,从而增强IαI的丝氨酸蛋白酶抑制活性,这在与炎症相关的蛋白酶网络中非常重要。这个基因可以由促炎细胞因子如肿瘤坏死因子α和白介素-1诱导。在骨关节炎和类风湿关节炎患者滑液中,这个蛋白质的水平升高。[RefSeq,2010年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
6
23749 bp
31.20
7
--
2
17

TNFAIP6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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