人类

TLR1 - Toll Like Receptor 1

Alias:
TIL
CD281
rsc786
TIL. LPRS5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Toll样受体(TLR)家族的一员,在病原体识别和先天免疫激活中起基本作用。TLRs从果蝇到人类高度保守,并在结构和功能上相似。它们识别感染剂上表达的病原体相关分子模式(PAMPs),并调节产生有效免疫发展所需的白细胞介素。各种TLR表现出不同的表达模式。这个基因被普遍表达,且表达水平高于其他TLR基因。已经注意到这个基因有不同的长度转录本,可能是由于使用替代的polyadenylation位点和/或替代的剪接所导致的。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
4
18076 bp
90.29
55
2
4
15

TLR1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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