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中文人类
TLN1 - Talin 1
Alias:
TLN
ILWEQ
talin-1
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这个基因编码一种细胞骨架蛋白，主要集中于细胞基底膜和细胞间接触区域。编码的蛋白质在肌动蛋白丝的组装和各种细胞类型的扩散和迁移中扮演重要角色，包括成纤维细胞和破骨细胞。它在细胞表面膜中与整合素共同分布，以协助粘附细胞与细胞外基质的附着以及淋巴细胞与其他细胞的附着。该蛋白质的N端含有定位到细胞-细胞外基质连接的元件。C端含有与β1整合素、肌动蛋白和vinculin等蛋白质的结合位点。[RefSeq，2009年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TLN1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
