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中文人类
TLE3 - TLE Family Member 3, Transcriptional Corepressor
Alias:
ESG
ESG3
GRG3
HsT18976
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这个基因编码一种属于转导样增强子家族蛋白的转录共阻遏蛋白。这个家族的成员在调节发育过程中细胞命运决定的Notch信号通路中发挥作用。这个基因的表达与卵巢癌患者对紫杉烷类化疗的有利结果有关。交替剪接导致多个转录变异体。已经描述了这个基因的其他交替剪接转录变异体，但它们的全长性质尚不清楚。[RefSeq, 2013年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TLE3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
