小鼠

P2ry12 - purinergic receptor P2Y, G-protein coupled 12

Alias:
P2Y12
2900079B22Rik
4921504D23Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活G蛋白偶联ADP受体活性和G蛋白偶联腺苷酸受体活性。参与多个过程,包括对ATP的细胞反应;调节小胶质细胞迁移;以及底物依赖的细胞迁移、细胞延伸。在多个过程的上游或内部发挥作用,包括腺苷酸环化酶调节G蛋白偶联受体信号通路;血小板激活;以及正调控离子运输。位于细胞体膜和细胞突起膜上。在中枢神经系统和大脑皮质中表达。用于研究血小板型出血障碍8。该基因的人类同源物涉及哮喘;脑血管疾病;外周动脉粥样硬化;血小板型出血障碍8;和2型糖尿病。与人类P2RY12(嘌呤能受体P2Y12)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
6
5
46717 bp
39.47
8
4

P2ry12 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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