Prpf3 - pre-mRNA processing factor 3

Predicted to enable identical protein binding activity. Predicted to be involved in spliceosomal tri-snRNP complex assembly. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in Cajal body; cytosol; and nuclear speck. Predicted to be part of U2-type precatalytic spliceosome and U4/U6 x U5 tri-snRNP complex. Is expressed in central nervous system; genitourinary system; gut gland; heart; and sensory organ. Used to study retinitis pigmentosa 18. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 18. Orthologous to human PRPF3 (pre-mRNA processing factor 3). [provided by Alliance of Genome Resources, Apr 2022]