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中文人类
TIE1 - Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1
Alias:
TIE
JTK14
LMPHM11
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这个基因编码酪氨酸蛋白激酶家族的一个成员。编码的蛋白质通过抑制血管生成素1通过内皮细胞受体酪氨酸激酶Tie2的信号通路，在血管生成和血管稳定性中发挥关键作用。编码蛋白质的外显子切割解除Tie2的抑制，并由包括血管内皮生长因子在内的多种因素介导。这个基因观察到了编码多个剪接变体的转录变体，这些剪接变体编码多个异构体。[由RefSeq提供，2011年11月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TIE1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
