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中文人类
TIA1 - TIA1 Cytotoxic Granule Associated RNA Binding Protein
Alias:
WDM
ALS26
TIA-1
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这个基因编码的产物是一个RNA结合蛋白家族的成员，并具有针对细胞毒性淋巴细胞（CTL）靶细胞的核酸酶活性。有研究表明，这种蛋白质可能参与诱导细胞凋亡，因为它优先识别poly(A)同聚物，并在CTL靶细胞中诱导DNA碎片。主要颗粒相关物种是一种15-kDa蛋白质，被认为是通过蛋白水解加工从40-kDa产物的羧基末端衍生而来的。已经发现这个基因存在导致不同异质体的可变剪接。[RefSeq提供，2017年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TIA1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
