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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
THBS4 - Thrombospondin 4
Alias:
TSP4
TSP-4
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质属于血栓素蛋白家族。血栓素家族成员是介导细胞间和细胞与基质相互作用的粘附糖蛋白。这种蛋白质形成五聚体,并能与肝素和钙结合。它参与发育和成年神经系统中的局部信号传导,并有助于脊髓敏感化和神经病理性疼痛状态。这个基因在侵入性乳腺癌的间质反应中被激活。它也可能在阿尔茨海默病的炎症反应中发挥作用。可变剪接导致多个转录变异体。[由RefSeq,2015年4月提供]
Related ID:
NCBI:7060
ENSEMBL:ENSG00000113296
HGNC:11788
UNIPROT:P35443
OMIM:600715
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7060
6
22
91956 bp
105.87
48
--
5
10
THBS4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Related Mouse Models
Type
Name
MGI
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Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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