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中文人类
TGM2 - Transglutaminase 2
Alias:
TGC
tTG
G(h)
hTG2
TG(C)
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转谷氨酰胺酶是一种催化蛋白质通过epsilon-gamma谷氨酰赖氨酸异肽键交联的酶。虽然转谷氨酰胺酶的初级结构不保守，但它们在活性部位都有相同的氨基酸序列，且其活性依赖于钙。此基因编码的蛋白质作为单体存在，被视黄酸诱导，并似乎涉及细胞凋亡。最后，该编码的蛋白质是自身抗原，与乳糜泻疾病有关。已发现此基因有两个转录变异体，编码不同的异构体。[RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TGM2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
