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中文人类
TG - Thyroglobulin
Alias:
TGN
AITD3
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甲状腺球蛋白（Tg）是一种主要由甲状腺产生的糖蛋白同二聚体。它作为甲状腺激素和三碘甲状腺原氨酸合成的底物，以及甲状腺激素和碘的惰性形式的储存。甲状腺球蛋白从内质网分泌到其碘化部位，然后在滤泡腔中进行后续的甲状腺激素生物合成。此基因的突变导致甲状腺激素异常产生，表现为甲状腺肿，并与中度至重度的先天性甲状腺功能减退症有关。此基因的多态性与自身免疫性甲状腺疾病（AITD）如格雷夫斯病和桥本甲状腺炎的易感性相关。[RefSeq,2009年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TG Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
