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中文人类
TEK - TEK Receptor Tyrosine Kinase
Alias:
TIE2
VMCM
GLC3E
TIE-2
VMCM1
CD202B
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这个基因编码一个属于蛋白质酪氨酸激酶Tie2家族的受体。编码的蛋白质具有一个独特的细胞外区域，包含两个免疫球蛋白样结构域，三个表皮生长因子（EGF）样结构域和三个纤维连接蛋白型III重复序列。配体血管生成素-1结合到这个受体上，并介导在胚胎血管发育中起作用的信号通路。这个基因的突变与皮肤和粘膜的遗传性静脉畸形有关。可变剪接导致多个转录变异体。这个基因的其他可变剪接转录变异体已经被描述过，但它们的全长性质尚不清楚。[由RefSeq，2014年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TEK Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
