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中文人类
BUB1B - BUB1 Mitotic Checkpoint Serine/threonine Kinase B
Alias:
MVA1
SSK1
BUBR1
Bub1A
MAD3L
hBUBR1
BUB1beta
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这个基因编码一个参与纺锤体检查点功能的激酶。这种蛋白质主要定位在动粒上，并在抑制促细胞分裂复合物/细胞质体（APC/C）方面发挥作用，延迟细胞分裂期的开始，并确保染色体正常分离。在许多类型的癌症中，纺锤体检查点功能受损。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BUB1B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
