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中文人类
TDO2 - Tryptophan 2,3-dioxygenase
Alias:
TO
TDO
TPH2
TRPO
HYPTRP
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这个基因编码一种血红素酶，在色氨酸代谢中起关键作用，催化犬尿氨酸途径的第一个限速步骤。编码蛋白质的活性增加和随后的犬尿氨酸产生也可能通过抑制抗肿瘤免疫反应在癌症中发挥作用，这个基因中的单核苷酸多态性可能与自闭症有关。[RefSeq，2012年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TDO2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
