Predicted to enable cell-cell adhesion mediator activity. Acts upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Located in adherens junction; bicellular tight junction; and plasma membrane. Is expressed in several structures, including cardiovascular system; liver; lung; nervous system; and placenta. Orthologous to human ESAM (endothelial cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]