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中文人类
VPS72 - Vacuolar Protein Sorting 72 Homolog
Alias:
YL1
CFL1
Swc2
YL-1
TCFL1
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这个基因编码的蛋白质是两种多组件复合物的共享亚基，分别是组蛋白乙酰转移酶复合物TRRAP/TIP60和包含染色质重塑蛋白SRCAP的复合物。TRRAP/TIP60复合物乙酰化核组蛋白，对转录调控、双链DNA断裂修复和凋亡具有重要意义。包含SRCAP的复合物催化组蛋白H2A与组蛋白变异体Htz1（H2AFZ）在核小体中的交换。这个蛋白质可能负责结合H2AFZ，后者在染色体分离中发挥作用。这个蛋白质还可能参与调节长期造血干细胞的活性。可变剪接产生多种编码不同蛋白质异型的转录变异体。[RefSeq，2012年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
VPS72 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
