Log In|Sign Up
中文人类
TBX5 - T-box Transcription Factor 5
Alias:
HOS
Favorite
这个基因是一个在系统发育上保守的基因家族成员，这些基因共享一个共同的DNA结合结构域，即T-box。T-box基因编码参与调控发育过程的转录因子。这个基因与相关家族成员T-box 3（尺骨乳腺综合征）在人染色体12上紧密连锁。编码的蛋白质可能在心脏发育和肢体特征指定中发挥作用。这个基因的突变与Holt-Oram综合征有关，这是一种影响心脏和上肢的发育紊乱。已描述了这个基因的几个转录变异体，编码不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TBX5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
