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中文人类
TAP1 - Transporter 1, ATP Binding Cassette Subfamily B Member
Alias:
APT1
PSF1
ABC17
ABCB2
PSF-1
RING4
TAP1N
D6S114E
TAP1*0102N
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这个基因编码的膜关联蛋白是ATP结合盒（ABC）转运蛋白超家族的一员。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族（ABC1，MDR/TAP，MRP，ALD，OABP，GCN20，White）。这个蛋白是MDR/TAP亚家族的一员。MDR/TAP亚家族的成员参与多药抗性。这个基因编码的蛋白参与将降解的胞质肽从内质网泵送到I类分子组装的膜结合腔室中。这个基因的突变可能与强直性脊柱炎、胰岛素依赖性糖尿病和乳糜泻疾病有关。已经发现这个基因有两个编码不同异型的转录变异体。[由RefSeq，2014年5月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TAP1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
