人类

TAF10 - TATA-box Binding Protein Associated Factor 10

Alias:
TAF2A
TAF2H
TAFII30
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
RNA聚合酶II的转录起始需要超过70种多肽的活动。协调这些活动的蛋白质是转录因子IID(TFIID),它结合核心启动子以正确定位聚合酶,作为转录复合物的其余部分组装的支架,并作为调节信号的通道。TFIID由TATA结合蛋白(TBP)和一组进化保守的蛋白质组成,称为TBP关联因子或TAFs。TAFs可能参与基础转录,作为协同激活物,在启动子识别中发挥作用,或者修改通用转录因子(GTFs)以促进复合物组装和转录起始。此基因编码与TFIID复合物子集相关联的TFIID的小亚单位之一。在人类和哺乳动物细胞中的研究表明,此亚单位对于雌激素受体的转录激活是必需的,对于细胞周期的进展是必需的,可能对于某些细胞分化程序也是必需的。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
5
5923 bp
21.71
324
--
2
19

TAF10 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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