Haspin - histone H3 associated protein kinase

Predicted to enable ATP binding activity; DNA binding activity; and histone kinase activity (H3-T3 specific). Predicted to be involved in histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; intracellular signal transduction; and mitotic sister chromatid cohesion. Predicted to act upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Predicted to be located in centrosome; nucleoplasm; and spindle. Predicted to be active in cytoplasm and nucleus. Orthologous to human HASPIN (histone H3 associated protein kinase). [provided by Alliance of Genome Resources, Apr 2022]