Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
TAF6 - TATA-box Binding Protein Associated Factor 6
Alias:
ALYUS
TAF2E
TAFII70
TAFII80
TAFII85
MGC:8964
TAFII-70
TAFII-80
TAF(II)70
TAF(II)80
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
RNA聚合酶II的转录起始需要超过70种多肽的活动。协调这些活动的蛋白质是转录因子IID(TFIID),它结合核心启动子以正确定位聚合酶,作为转录复合物的其余部分组装的支架,并作为调节信号的通道。TFIID由TATA结合蛋白(TBP)和一组进化保守的蛋白质组成,称为TBP相关因子或TAFs。TAFs可能参与基础转录,作为协同激活物,在启动子识别中发挥作用,或者修改通用转录因子(GTFs)以促进复合物组装和转录起始。此基因编码TFIID的较小亚基之一,该亚基与TBP弱结合,但与TFIID的最大亚基TAF1强结合。可变剪接导致多个转录变异体。[RefSeq,2010年6月提供]
Related ID:
NCBI:6878
ENSEMBL:ENSG00000106290
HGNC:11540
UNIPROT:P49848
OMIM:602955
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6878
17
15
20102 bp
72.67
115
4
4
27
TAF6 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top