Tnfaip3 - TNF alpha induced protein 3

Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; deubiquitinase activity; and enzyme binding activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; negative regulation of signal transduction; and protein modification by small protein conjugation or removal. Predicted to act upstream of or within several processes, including negative regulation of interleukin-1 beta production; positive regulation of cellular protein catabolic process; and protein K63-linked deubiquitination. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in familial Behcet-like autoinflammatory syndrome. Orthologous to human TNFAIP3 (TNF alpha induced protein 3). [provided by Alliance of Genome Resources, Apr 2022]