Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation from RNA polymerase II promoter. Predicted to be located in cytosol and nuclear speck. Predicted to be part of transcription factor TFIID complex and transcription factor TFIIE complex. Is expressed in several structures, including alimentary system; blastocyst; central nervous system; genitourinary system; and liver lobe. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 6. Orthologous to human GTF2E2 (general transcription factor IIE subunit 2). [provided by Alliance of Genome Resources, Apr 2022]