Lemd3 - LEM domain containing 3

Predicted to enable chromatin DNA binding activity. Predicted to be involved in negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway and nuclear envelope organization. Predicted to act upstream of or within several processes, including blood vessel endothelial cell migration involved in intussusceptive angiogenesis; regulation of extracellular matrix organization; and skeletal muscle cell differentiation. Predicted to be located in nuclear inner membrane. Predicted to be integral component of membrane. Predicted to be integral component of nuclear inner membrane. Human ortholog(s) of this gene implicated in Buschke-Ollendorff syndrome. Orthologous to human LEMD3 (LEM domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]