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Tcf7l2 - transcription factor 7 like 2

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测具有多种功能,包括:DNA结合转录激活因子活性,特异性为RNA聚合酶II;臂状重复结构域结合活性;以及β-联蛋白结合活性。参与细胞凋亡过程的负调控和RNA聚合酶II驱动的转录调控。预测位于染色质;细胞质;和核质中。预测是β-联蛋白-TCF7L2复合物和蛋白质-DNA复合物的一部分。2型糖尿病的生物标志物。该基因的人类同源物与结直肠癌、糖尿病(多种类型)、胰腺癌和前列腺癌有关。与人类TCF7L2(转录因子7类似2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
49
15
193012 bp
Unknown
19
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Tcf7l2 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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