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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Tcf7l2 - transcription factor 7 like 2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测具有多种功能,包括:DNA结合转录激活因子活性,特异性为RNA聚合酶II;臂状重复结构域结合活性;以及β-联蛋白结合活性。参与细胞凋亡过程的负调控和RNA聚合酶II驱动的转录调控。预测位于染色质;细胞质;和核质中。预测是β-联蛋白-TCF7L2复合物和蛋白质-DNA复合物的一部分。2型糖尿病的生物标志物。该基因的人类同源物与结直肠癌、糖尿病(多种类型)、胰腺癌和前列腺癌有关。与人类TCF7L2(转录因子7类似2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:679869
ENSEMBL:ENSRNOG00000049232
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
679869
49
15
193012 bp
Unknown
19
--
Tcf7l2 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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