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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
STK10 - Serine/threonine Kinase 10
Alias:
LOK
PRO2729
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码Ste20家族丝氨酸/苏氨酸蛋白激酶成员,与几个已知的类似Polo的激酶类似。该蛋白可以与Polo样激酶1结合并进行磷酸化,而激酶失活版本的过表达会干扰正常的细胞周期进程。该激酶还可以通过有丝分裂原激活的蛋白激酶激酶1途径负调节T细胞中的白细胞介素2表达。[由RefSeq,2008年7月提供]
Related ID:
NCBI:6793
ENSEMBL:ENSG00000072786
HGNC:11388
UNIPROT:O94804
OMIM:603919
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6793
4
19
146146 bp
112.14
49
1
4
25
STK10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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