人类

STAT2 - Signal Transducer And Activator Of Transcription 2

Alias:
P113
IMD44
ISGF-3
PTORCH3
STAT113
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是STAT蛋白质家族的一员。响应细胞因子和生长因子,STAT家族成员被受体相关激酶磷酸化,然后形成同源或异源二聚体,转移到细胞核中作为转录激活子发挥作用。响应干扰素(IFN),这个蛋白质与STAT1和IFN调节因子家族蛋白质p48(ISGF3G)形成复合物,其中这个蛋白质作为转激活子发挥作用,但缺乏直接结合DNA的能力。这个蛋白质介导天生的抗病毒活性。这个基因的突变导致免疫缺陷44。[由RefSeq,2020年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
15
24
18511 bp
97.92
393
3
11
39

STAT2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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