Rnf149 - ring finger protein 149

Enables ubiquitin protein ligase activity. Acts upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human RNF149 (ring finger protein 149). [provided by Alliance of Genome Resources, Apr 2022]