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中文人类
SSRP1 - Structure Specific Recognition Protein 1
Alias:
FACT
T160
FACT80
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这个基因编码的蛋白质是异源二聚体的亚基，该二聚体与SUPT16H一起形成染色质转录延长因子FACT。FACT特异性地与组蛋白H2A/H2B相互作用，以影响核小体的解体和转录延长。FACT和顺铂损伤的DNA可能是顺铂抗癌机制的关键。这个编码的蛋白质包含一个高移动组盒，这很可能是顺铂修饰的DNA的结构识别元素。这个蛋白质也作为转录激活子p63的辅助激活子发挥作用。已经描述了这个基因的一个可变剪接转录变异体，但其完整的长度尚不清楚。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SSRP1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
