Log In|Sign Up
中文人类
SREBF1 - Sterol Regulatory Element Binding Transcription Factor 1
Alias:
HMD
IFAP2
SREBP1
bHLHd1
Favorite
这个基因编码一个结合固醇调节元件-1(SRE1)的基本螺旋-环-螺旋-亮氨酸拉链(bHLH-Zip)转录因子，SRE1是一个存在于低密度脂蛋白受体基因和其他参与固醇生物合成的基因启动子中的基序。编码的蛋白质最初附着在核膜和内质网作为前体合成。切割后，成熟蛋白质转运到核糖体并激活转录。这一切割过程受到固醇的抑制。这个基因位于染色体17的Smith-Magenis综合征区域。可选的启动子使用和剪接导致多个转录变异体，包括SREBP-1a和SREBP-1c，它们分别对应于RefSeq转录本变异体2和3。[由RefSeq，2017年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SREBF1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
