Predicted to enable NADH dehydrogenase (ubiquinone) activity. Acts upstream of or within extrinsic apoptotic signaling pathway. Located in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 28 and thyroid gland Hurthle cell carcinoma. Orthologous to several human genes including NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13). [provided by Alliance of Genome Resources, Apr 2022]