Nradd - neurotrophin receptor associated death domain

Predicted to enable several functions, including death receptor activity; nerve growth factor binding activity; and neurotrophin p75 receptor binding activity. Predicted to be involved in Rho protein signal transduction and positive regulation of cell death. Predicted to act upstream of or within apoptotic process. Located in lamellipodium; membrane; and nuclear envelope lumen. Is expressed in medulla oblongata and medulla oblongata basal plate mantle layer. Orthologous to human NRADDP (neurotrophin receptor associated death domain, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]