人类

SRC - SRC Proto-oncogene, Non-receptor Tyrosine Kinase

Alias:
ASV
SRC1
THC6
c-SRC
p60-Src
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因与Rous肉瘤病毒的v-src基因高度相似。这个原癌基因可能在胚胎发育和细胞生长的调节中发挥作用。这个基因编码的蛋白质是一种酪氨酸蛋白激酶,其活性可以通过c-SRC激酶的磷酸化来抑制。这个基因的突变可能涉及结肠癌的恶性进展。已经发现这个基因有两个转录变异体,它们编码相同的蛋白质。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
21
14
61352 bp
59.84
62
2
13
81

SRC Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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