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中文人类
SPI1 - Spi-1 Proto-oncogene
Alias:
OF
PU.1
AGM10
SFPI1
SPI-1
SPI-A
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这个基因编码一个在髓样和B淋巴细胞发育过程中激活基因表达的ETS域转录因子。该核蛋白结合到称为PU-box的富含嘌呤序列，该序列位于目标基因的启动子附近，并与其他转录因子和辅助因子协同调节它们的表达。该蛋白还可以调节目标基因的替代剪接。已发现这个基因的多个转录变异体，编码不同的异构体。[RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SPI1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
