Predicted to enable enzyme binding activity. Acts upstream of or within hydrogen peroxide metabolic process; regulation of inflammatory response; and regulation of thyroid hormone generation. Predicted to be located in several cellular components, including apical part of cell; cell leading edge; and endoplasmic reticulum. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in thyroid dyshormonogenesis 5. Orthologous to human DUOXA2 (dual oxidase maturation factor 2). [provided by Alliance of Genome Resources, Apr 2022]