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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SP2 - Sp2 Transcription Factor
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码Sp/XKLF转录因子亚家族Sp亚家族的成员。Sp家族蛋白是序列特异性的DNA结合蛋白,其特征是具有氨基端反式激活结构和三个羧基端锌指结构。这个蛋白含有Sp亚家族蛋白中最保守的DNA结合结构域,其DNA序列特异性与其他Sp蛋白不同。它主要定位在与核基质相关的亚核焦点内,可以激活或在某些情况下抑制不同启动子的表达。[由RefSeq,2008年7月提供]
Related ID:
NCBI:6668
ENSEMBL:ENSG00000167182
HGNC:11207
UNIPROT:Q02086
OMIM:601801
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6668
19
7
35496 bp
64.90
19
--
8
9
SP2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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CDS(bp)
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Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Name
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References Literature
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