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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
FSCN1 - Fascin Actin-bundling Protein 1
Alias:
HSN
SNL
p55
FAN1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码肌动蛋白结合蛋白家族成员之一。Fascin蛋白将F-肌动蛋白组织成平行束,并且对于基于肌动蛋白的细胞突起形成是必需的。编码的蛋白质在细胞迁移、迁移性、粘附和细胞相互作用中扮演关键角色。已知这个基因的表达受到几种微小RNA的调节,并且这个基因的过度表达可能通过增加细胞迁移性在多种癌症的转移中发挥作用。这个基因的表达也是霍奇金淋巴瘤中里德-斯特恩伯格细胞的标志。这个基因的一个假基因位于染色体15的长臂上。[由RefSeq,2011年9月提供]
Related ID:
NCBI:6624
ENSEMBL:ENSG00000075618
HGNC:11148
UNIPROT:Q16658
OMIM:602689
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6624
1
5
13840 bp
54.53
14
--
5
24
FSCN1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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Transcript
Length(nt)
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Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Name
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CAS Number
Status
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Link
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References Literature
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