Eef1e1 - eukaryotic translation elongation factor 1 epsilon 1

Involved in negative regulation of cell population proliferation and positive regulation of apoptotic process. Acts upstream of or within cellular response to leukemia inhibitory factor; positive regulation of DNA damage response, signal transduction by p53 class mediator; and positive regulation of apoptotic signaling pathway. Located in cytoplasm and nucleus. Part of aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including central nervous system and retina. Orthologous to human EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1). [provided by Alliance of Genome Resources, Apr 2022]