人类

SIGLEC1 - Sialic Acid Binding Ig Like Lectin 1

Alias:
SN
CD169
SIGLEC-1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码免疫球蛋白超家族的一员。编码的蛋白质是一种凝集素样的粘附分子,以唾液酸依赖的方式结合细胞表面的糖复合物配体。它是一种I型跨膜蛋白,仅由一部分巨噬细胞表达,并涉及调节细胞间相互作用。该蛋白质在多种人类疾病、细菌和病毒感染中扮演重要角色,已被证明能增强SARS-CoV-2感染。[由RefSeq,2021年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
22
25631 bp
182.62
111
--
13
10

SIGLEC1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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