Txndc12 - thioredoxin domain containing 12 (endoplasmic reticulum)

Predicted to enable protein-disulfide reductase activity. Predicted to be involved in negative regulation of cell death. Predicted to act upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cranium; eye; and respiratory system. Orthologous to human TXNDC12 (thioredoxin domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]