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中文人类
BMX - BMX Non-receptor Tyrosine Kinase
Alias:
ETK
PSCTK2
PSCTK3
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这个基因编码一个属于Tec激酶家族的非受体酪氨酸激酶。该蛋白质包含一个PH样结构域，通过结合磷酸atylinositol 3,4,5-三磷酸(PIP3)来调节膜定位，以及一个SH2结构域，可以结合酪氨酸磷酸化蛋白质，并在信号传导中发挥作用。该蛋白质与几个信号传导途径有关，包括Stat途径，并调节几种类型癌细胞的不同化和肿瘤形成能力。已经发现这个基因的替代剪接转录变异体。[RefSeq,2016年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BMX Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
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Phase
Link
References Literature
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PMID
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Year
IF
