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中文人类
BMPR1A - Bone Morphogenetic Protein Receptor Type 1A
Alias:
ALK3
SKR5
ALK-3
CD292
ACVRLK3
BMPR-1A
10q23del
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骨形态发生蛋白（BMP）受体是一类跨膜丝氨酸/苏氨酸激酶家族，包括I型受体BMPR1A和BMPR1B以及II型受体BMPR2。这些受体也与激活素受体ACVR1和ACVR2有密切关系。这些受体的配体是TGF-beta超家族的成员。TGF-betas和activins通过与两种不同类型的丝氨酸（苏氨酸）激酶受体形成异源复合物来传递它们的信号：约50-55kD的I型受体和约70-80kD的II型受体。II型受体在无I型受体存在下结合配体，但它们需要各自的I型受体进行信号传递，而I型受体需要各自的II型受体进行配体结合。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BMPR1A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
