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中文人类
SLC10A1 - Solute Carrier Family 10 Member 1
Alias:
NTCP
FHCA2
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这个基因编码的蛋白质属于钠/胆汁酸共同转运体家族，这些整合膜糖蛋白参与胆汁酸的自肝循环。两个同源转运体涉及胆汁酸的重吸收；回肠钠/胆汁酸共同转运体具有顶细胞定位，从肠道腔、胆管和肾脏吸收胆汁酸，以及由该蛋白质代表的肝脏特异性的钠/胆汁酸共同转运体，位于肝细胞基底侧膜中。胆汁酸是胆固醇代谢的分解产物，因此该蛋白质对胆固醇内稳态非常重要。[由RefSeq，2011年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SLC10A1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
