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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
YTHDC2 - YTH N6-methyladenosine RNA Binding Protein C2
Alias:
CAHL
hYTHDC2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码DEAH(Asp-Glu-Ala-His)亚家族蛋白质的一员,属于DEAD(Asp-Glu-Ala-Asp)盒RNA解旋酶家族。编码的蛋白质与N6-甲基腺苷结合,这是一种常见的修饰RNA核苷酸,丰富存在于真核信使RNA的终止密码子和3'UTRs中。蛋白质与这种修饰核苷酸的结合可能调节mRNA的翻译和稳定性。这个基因可能与人类患者胰腺癌的易感性有关,并且这个基因的敲除导致一个人类肝癌细胞系中的增殖减少。[由RefSeq,2016年9月提供]
Related ID:
NCBI:64848
ENSEMBL:ENSG00000047188
HGNC:24721
UNIPROT:Q9H6S0
OMIM:616530
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
64848
9
30
81591 bp
160.25
54
--
16
15
YTHDC2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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No data available
Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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References Literature
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