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中文人类
SHMT1 - Serine Hydroxymethyltransferase 1
Alias:
SHMT
CSHMT
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这个基因编码胞质形式的血清羟甲基转移酶，这是一种含有吡哆醇磷酸酶的酶，可催化丝氨酸和四氢叶酸可逆地转化为甘氨酸和5,10-亚甲基四氢叶酸。这个反应为甲硫氨酸、胸苷酸盐和胞浆中嘌呤的合成提供一碳单位。这个基因位于染色体17的Smith-Magenis综合征区域内。这个基因的一个假基因位于染色体1的短臂上。选择性剪接导致多个转录变异体。[RefSeq，2013年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SHMT1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
