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中文人类
CLEC7A - C-type Lectin Domain Containing 7A
Alias:
BGR
CD369
CANDF4
SCARE2
DECTIN1
CLECSF12
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这个基因编码C-型凝集素/C-型凝集素样结构域（CTL/CTLD）超家族的一员。编码的糖蛋白是一个小型II型膜受体，具有细胞外的C-型凝集素样结构域折叠和具有免疫受体酪氨酸激活基序的胞质结构域。它作为模式识别受体发挥作用，识别来自真菌和植物的多种β-1,3连接和β-1,6连接的葡聚糖，以这种方式在天然免疫应答中发挥作用。已表征了替代转录剪接变异体，编码不同的异构体。这个基因与其他CTL/CTLD超家族成员在染色体12p13的自然杀伤基因复合体区域紧密连锁。[RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CLEC7A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
