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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Ctsb - cathepsin B
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括半胱氨酸型内肽酶活性;激肽原结合活性;和蛋白质自聚集。参与多种过程,包括细胞对机械刺激的响应;对乙醇的响应;和对白细胞介素-4的响应。位于几个细胞成分中,包括顶浆膜;浆膜的外侧;和肌内膜。与 caveola 和细胞质核周区域共定位。用于研究肝细胞癌和高等级神经胶质瘤。几种疾病的生物标志物,包括急性坏死性胰腺炎;脑血管疾病(多种);钩虫病;脂肪肝病;和肾小管性酸中毒。该基因的人类同源物与糖尿病有关。与人类 CTSB(组织蛋白酶 B)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:64529
ENSEMBL:ENSRNOG00000010331
UNIPROT:P00787
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
64529
1
10
20873 bp
Unknown
5
3
Ctsb Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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